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Klaus Wrogemann Selected Research

Limb-girdle muscular dystrophy type 2H

9/2006The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.
4/2005Commonality of TRIM32 mutation in causing sarcotubular myopathy and LGMD2H.
3/2002Limb-girdle muscular dystrophy type 2H associated with mutation in TRIM32, a putative E3-ubiquitin-ligase gene.

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Klaus Wrogemann Research Topics

Disease

3Limb-girdle muscular dystrophy type 2H
09/2006 - 03/2002
1Intellectual Disability (Idiocy)
09/2011
1Carcinogenesis
09/2006
1Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl)
09/2006
1Type 2I Limb-Girdle Muscular Dystrophy
01/2005
1Cardiomegaly (Heart Hypertrophy)
01/2005
1Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
11/2004

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
09/2011 - 11/2004
1Fatty Acids (Saturated Fatty Acids)IBA
09/2011
1Ligases (Synthetase)IBA
09/2006
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2006
1UbiquitinIBA
09/2006
1Creatine Kinase (Creatine Phosphokinase)IBA
01/2005
1Aspartic Acid (Aspartate)FDA Link
03/2002
1AsparagineIBA
03/2002

Therapy/Procedure

1General Anesthesia
01/2005